Simulation of Field-Effect Biosensors (BioFETs) for Biotin-Streptavidin Complexes

نویسندگان

  • Thomas Windbacher
  • Viktor Sverdlov
  • Siegfried Selberherr
  • Clemens Heitzinger
  • Norbert Mauser
  • Christian Ringhofer
چکیده

Biologically sensitive field-effect transistors (BioFETs) are a promising technology for detecting pathogens, antigen-antibody complexes, and tumor markers. A BioFET is studied for a biotin-streptavidin complex. Biotin-streptavidin is used in detection and purification of various biomolecules. The link between the Angstrom scale of the chemical reaction and the micrometer scale of the field effect device is realized by homogenized interface conditions.

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تاریخ انتشار 2009